Progressive ataxia with palatal tremor (PAPT)
Evidence-based neurology checklist on progressive ataxia with palatal tremor (papt): Pathology This is a form of symptomatic palatal tremor It is associated with progressive cerebellar degeneration Familial cases may have brainstem, cerebellar, and cervical cord atrophy Glial fibrillary acidic…
Pathology
- This is a form of symptomatic palatal tremor
- It is associated with progressive cerebellar degeneration
- Familial cases may have brainstem, cerebellar, and cervical cord atrophy
- Glial fibrillary acidic protein (GFAP) gene substitution has been reported
Clinical features
Neurodegenerative causes
Magnetic resonance imaging (MRI) brain
References
- Samual M, Torun N, Tuite PJ, Sharpe JA, Lang AE. Progressive ataxia and palatal tremor (PAPT): clinical and MRI assessment with review of palatal tremors. Brain 2004; 127:1252-1268.
- Rossi M, Cesarini M, Gatto EM, Cammarota A, Merello M. A treatable rare cause of progressive ataxia and palatal tremor. Tremor Other Hyperkinet Mov (N Y) 2018; 8:538.
