Primary lateral sclerosis (PLS): investigations
Evidence-based neurology checklist on primary lateral sclerosis (pls): investigations: Neurophysiology Electromyogram (EMG) is abnormal Nerve conduction studies (NCS): this shows minor sensory features Magnetic resonance imaging (MRI): features Magnetic resonance spectroscopy (MRS): features…
Neurophysiology
- Electromyogram (EMG) is abnormal
- Nerve conduction studies (NCS): this shows minor sensory features
Magnetic resonance imaging (MRI): features
Magnetic resonance spectroscopy (MRS): features
Genetic tests
Emerging investigations
References
- Pringle CE, Hudson AJ, Munoz DG, et al. Primary lateral sclerosis: clinical features, neuropathology and diagnostic criteria. Brain 1992; 115:495-520.
- Turner MR, Barohn RJ, Corcia P, et al. Primary lateral sclerosis: consensus diagnostic criteria. JNNP 2020; 91:373-377.
- Zhai P, Pagan F, Statland J, Butman JA, Floeter MK. Primary lateral sclerosis: a heterogenous disorder composed of different subtypes. Neurology 2003; 60:1258-1265.
