Primary lateral sclerosis (PLS): differential diagnosis

Evidence-based neurology checklist on primary lateral sclerosis (pls): differential diagnosis: Infectious differentials Syphilis Lyme disease HTLV: tropical spastic paraparesis (TSP) Brucellosis HIV Other differentials

Infectious differentials

  • Syphilis
  • Lyme disease
  • HTLV: tropical spastic paraparesis (TSP)
  • Brucellosis
  • HIV

Other differentials

References

  1. Pringle CE, Hudson AJ, Munoz DG, et al. Primary lateral sclerosis: clinical features, neuropathology and diagnostic criteria. Brain 1992; 115:495-520.
  2. Turner MR, Barohn RJ, Corcia P, et al. Primary lateral sclerosis: consensus diagnostic criteria. JNNP 2020; 91:373-377.

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