Primary amoebic meningoencephalitis (PAM): management
Evidence-based neurology checklist on primary amoebic meningoencephalitis (pam): management: Cerebrospinal fluid (CSF) analysis Raised opening pressure Neutrophilic pleocytosis Low glucose High protein Motile N. fowleri Giemsa or Wright stains for trophozoites Positive enflagellation test Magnetic…
Cerebrospinal fluid (CSF) analysis
- Raised opening pressure
- Neutrophilic pleocytosis
- Low glucose
- High protein
- Motile N. fowleri
- Giemsa or Wright stains for trophozoites
- Positive enflagellation test
Magnetic resonance imaging (MRI) brain: features
Primary treatment
Possible adjunctive treatments
Prophylaxis
References
- Siddiqui R, Khan NA. Primary amoebic meningoencephalitis caused by Naegleria fowleri: an old enemy presenting new challenges. PLoS Negl Trop Dis 2014; 8:e3017.
- Grace E, Asbill S, Virga K. Naegleria fowleri: pathogenesis, diagnosis, and treatment options. Antimicrob Agents Chemother 2015; 59:6677-6681.
- Capewell LG, Harris AM, Yoder JS, et al. Diagnosis, clinical course, and treatment of primary amoebic meningoencephalitis in the United States, 1937-2013. J Pediatric Infect Dis Soc 2015; 4:e68-e75.
