Peripheral nerve hyperexcitability (PNH): clinical features

Evidence-based neurology checklist on peripheral nerve hyperexcitability (pnh): clinical features: Onset features The average onset age is in the 5th decade The onset age may be as young as 9 years Exercise-induced hyperexcitability symptoms Other muscle features Sensory features Central features…

Onset features

  • The average onset age is in the 5th decade
  • The onset age may be as young as 9 years

Exercise-induced hyperexcitability symptoms

Other muscle features

Sensory features

Central features

Psychiatric features

References

  1. Hart IK, Maddison P, Newsome-Davis J, Vincent A, Mills KR. Phenotypic variants of autoimmune peripheral nerve hyperexcitability. Brain 2002; 125:1887-1895.
  2. Rubio-Agusti I, Perez-Miralles F, Sevilla T, et al. Peripheral nerve hyperexcitability: a clinical and immunological study of 38 patients. Neurology 2011; 76:172-178.
  3. Camelo CG, Silva AMS, Moreno CAM, et al. Facial myokymia in inherited peripheral nerve hyperexcitability syndrome. Pract Neurol 2020; 20:253-255. 

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