Periodic limb movements in sleep (PLMS)

Evidence-based neurology checklist on periodic limb movements in sleep (plms): Classification Type I: spontaneous: worse in the early sleep period Type II: secondary: uniformly spread throughout the sleep period Risk genes: for type I PLMS Diagnostic criteria Clinical features Associated symptoms…

Classification

  • Type I: spontaneous: worse in the early sleep period
  • Type II: secondary: uniformly spread throughout the sleep period

Risk genes: for type I PLMS

Diagnostic criteria

Clinical features

Associated symptoms

Associated neurological disorders

Associated systemic disorders

Potential drug triggers

Possible complications

Differential diagnosis

Investigations

Treatment

Old synonym

References

  1. Choi JW, Song JS, Lee YJ, Jeong DU. Periodic limb movements in sleep is associated with increased mortality. Psychiatry Investig 2017; 14:669-673.
  2. Natarajan R. Review of periodic limb movement and restless leg syndrome. J Postgrad Med 2010; 56:157-162.
  3. Winkelman JW, Blackwell T, Stone K, et al. Genetic associations of periodic limb movements of sleep in the elderly for the MrOS sleep study. Sleep Med 2015; 16:1360-1365.
  4. Moore H 4th, Winkelmann J, Lin L, Finn L, Peppard P, Mignot E. Periodic leg movements during sleep are associated with polymorphisms in BTBD9, TOX3/BC034767, MEIS1, MAP2K5/SKOR1, and PTPRD. Sleep 2014; 37:1535-1542.
  5. Stefani A, Heidbreder A, Hackner H, Högl B. Validation of a leg movements count and periodic leg movements analysis in a custom polysomnography system. BMC Neurol 2017; 17:42.
  6. And 26 more. Subscribe to see the full list

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