Painful legs moving toes (PLMT)

Causes

• Idiopathic
• Peripheral neuropathy (PN)
• Radiculopathies e.g. Herpes zoster
• Myelitis
• Cauda equina lesions 
• Nerve root lesions
• Neuroleptics
• Chemotherapy
• Wilson's disease
• Systemic diseases e.g. HIV
• Dementia with Lewy bodies (DLB)

Types

Clinical features

Variants

Drug treatments

Non-drug treatments

References

1. Liu R, Moizuddin M, Hung S. Painful legs and moving toes-case report and review of the literature. BJMP 2011; 4:a431.
2. Renard D, Taieb G, Castelnovo G, Labauge P. Teaching Video Neuroimages: Painful legs, moving toes associated with partial transverse myelitis. Neurology 2010; 75:e74.
3. Madokoro Y, Mizuno M, Kawashima S, Okita K, Matsukawa N. Painful legs and moving toes syndrome associated with dementia with Lewy bodies responsive to rotigotine-induced analgesia. Neurol Sci 2022; 43:6569-6570. 
4. Schoenen J, Gonce M, Delwaide PJ. Painful legs and moving toes: a syndrome with different physiopathologic mechanisms. Neurology (Cleveland) 1984; 34:1108-1112.
5. Miyakawa T, Yoshimoto M, Takebayashi T, Yamashita T. Case Reports: Painful limbs/moving extremities: report of two cases. Clin Orthop Relat Res 2010; 468:3419-3425.
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Related checklists

• Periodic limb movements in sleep (PLMS)
• Alien limb syndrome
• Motor stereotypy disorders
• Myorrhythmia
• Mirror movements
• Sandifer syndrome
• Tongue movement disorders