Paroxysmal sympathetic hyperactivity (PSH)

Description

• This is the occurrence of periodic symptoms
• It usually develops after traumatic brain injury (TBI)
• The symptoms may last several months
• It may be predicted by early fever after TBI

Diagnostic criteria

Associated features

Causes

Drug treatments

Supportive treatments

References

1. Meyfroidt G, Baguley IJ, Menon DK. Paroxysmal sympathetic hyperactivity: the storm after acute brain injury. Lancet Neurol 2017; 16:721-729.
2. Hinson HE, Schreiber MA, Laurie AL, Baguley IJ, Bourdette D, Ling GSF. Early fever as a predictor of paroxysmal sympathetic hyperactivity in traumatic brain injury. J Head Trauma Rehabil 2017; 32:E50-E54.
3. Krupanandan R. Paroxysmal sympathetic hyperactivity: it is time to use the new diagnostic criteria. Indian J Crit Care Med 2022; 26:1165-1166.
4. Gupta HV, Sharma VD, Espay AJ. The pseudodystonia of paroxysmal sympathetic hyperactivity: a reversible post-anoxic complication. Mov Disord Clin Pract 2020; 7:987-989.
5. Siahaan AMP, Tandean S, Indharty RS, Nainggolan BWM, Susanto M. Paroxysmal sympathetic hyperactivity syndrome in tuberculous meningitis with paradoxical reaction. Int J Surg Case Rep 2022; 99:107619.
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Related checklists

• Post-concussion syndrome (PCS)
• Post traumatic headache (PTH)
• Post-traumatic hypopituitarism (PTHP)