Parkinson's disease (PD) in women

Evidence-based neurology checklist on parkinson's disease (pd) in women: Demographic features PD is less frequent in women than in men: the ratio is 1:2 It starts at a later onset age in women than in men It is more likely to be tremor-dominant in women It progresses more slowly in women Levodopa…

Demographic features

  • PD is less frequent in women than in men: the ratio is 1:2
  • It starts at a later onset age in women than in men
  • It is more likely to be tremor-dominant in women
  • It progresses more slowly in women
  • Levodopa is more bioavailable in women
  • Women have a better quality of life after deep brain stimulation (DBS)

PD features which are more common in women

PD features that are less common in women

Factors worsening PD symptoms in women

PD management in pregnancy

References

  1. Picillo M, Nicoletti A, Fetoni V, Garavaglia B, Barone P, Pellecchia MT. The relevance of gender in Parkinson's disease: a review. J Neurol 2017; 264:1583-1607. 
  2. Georgiev D, Hamberg K, Hariz M, Forsgren L, Hariz GM. Gender differences in Parkinson's disease: a clinical perspective. Acta Neurol Scand 2017; 136:570-584. 
  3. Rabin ML, Stevens-Haas C, Havrilla E, Devi T, Kurlan R. Movement disorders in women: a review. Mov Disord 2014; 29:177-183.
  4. Wooten GF, Currie LJ, Bovbjerg VE, Lee JK, Patrie J. Are men at greater risk for Parkinson's disease than women? JNNP 2004; 75:637-639.
  5. Haaxma CA, Bloem BR, Borm GF, et al. Gender differences in Parkinson's disease. JNNP 2007; 78:819-824. 
  6. And 10 more. Subscribe to see the full list

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