Osmotic demyelination disorders (ODD): treatment
Evidence-based neurology checklist on osmotic demyelination disorders (odd): treatment: Correction of hyponatraemia Correct hyponatraemia slowly This is usually done at a rate of <6-8 mmol/L per 24-hour period A slower rate of 4-6 mmol/L in 24 hours is indicated in high-risk individuals…
Correction of hyponatraemia
- Correct hyponatraemia slowly
- This is usually done at a rate of <6-8 mmol/L per 24-hour period
- A slower rate of 4-6 mmol/L in 24 hours is indicated in high-risk individuals
Potentially beneficial treatments
References
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- Kumar S, Fowler M, Gonzalez-Toledo E, Jaffe SL. Central pontine myelinolysis, an update. Neurol Res 2006; 28:360-366.
- Deleu D, Salim K, Mesraoua B, El Siddig A, Al Hail H, Hanssens Y. "Man-in-the-barrel" syndrome as delayed manifestation of extrapontine and central pontine myelinolysis: beneficial effect of intravenous immunoglobulin. J Neurol Sci 2005; 237:103-106.
- Parejo-Sánchez MI, Pardo-Cabello AJ, Manzano-Gamero MV, de Luna-Sánchez S. Favourable response to the use of intravenous immunoglobulins in central pontine myelinolysis. Rev Neurol 2013; 57:144.