Osmotic demyelination disorders (ODD): treatment

Evidence-based neurology checklist on osmotic demyelination disorders (odd): treatment: Correction of hyponatraemia Correct hyponatraemia slowly This is usually done at a rate of <6-8 mmol/L per 24-hour period A slower rate of 4-6 mmol/L in 24 hours is indicated in high-risk individuals…

Correction of hyponatraemia

  • Correct hyponatraemia slowly
  • This is usually done at a rate of <6-8 mmol/L per 24-hour period
  • A slower rate of 4-6 mmol/L in 24 hours is indicated in high-risk individuals

Potentially beneficial treatments

References

  1. Ahmad G, Vassallo J, Naqvi J, Khanna N. An unusual case of quadriparesis. BMJ 2013; 347:f5728.
  2. Kumar S, Fowler M, Gonzalez-Toledo E, Jaffe SL. Central pontine myelinolysis, an update. Neurol Res 2006; 28:360-366.
  3. Deleu D, Salim K, Mesraoua B, El Siddig A, Al Hail H, Hanssens Y. "Man-in-the-barrel" syndrome as delayed manifestation of extrapontine and central pontine myelinolysis: beneficial effect of intravenous immunoglobulin. J Neurol Sci 2005; 237:103-106.
  4. Parejo-Sánchez MI, Pardo-Cabello AJ, Manzano-Gamero MV, de Luna-Sánchez S. Favourable response to the use of intravenous immunoglobulins in central pontine myelinolysis. Rev Neurol 2013; 57:144.

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