Osmotic demyelination disorders (ODD): investigations

Evidence-based neurology checklist on osmotic demyelination disorders (odd): investigations: Magnetic resonance imaging (MRI) This demonstrates the omega sign or the trident sign This is a symmetrical central area of triangular pontine demyelination It is hyperintense on T2 and hypointense on T1…

Magnetic resonance imaging (MRI)

  • This demonstrates the omega sign or the trident sign
  • This is a symmetrical central area of triangular pontine demyelination
  • It is hyperintense on T2 and hypointense on T1 sequences
  • The outer pontine rim is normal
  • MRI may also show the piglet sign in the upper pons

References

  1. Biotti D, Durupt D. A trident in the brain, central pontine myelinolysis. Pract Neurol 2009; 9:231-232.
  2. Ahmad G, Vassallo J, Naqvi J, Khanna N. An unusual case of quadriparesis. BMJ 2013; 347:f5728.
  3. Tan H, Onbaş O. Central pontine myelinolysis manifesting with massive myoclonus. Pediatr Neurol 2004; 31:64-66.
  4. Beh SC. Temporal evolution of the trident and piglet signs of osmotic demyelination syndrome. J Neurol Sci 2017; 373:268-273.

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