Neuropsychiatric systemic lupus erythematosus (NPSLE): investigations

Evidence-based neurology checklist on neuropsychiatric systemic lupus erythematosus (npsle): investigations: Autoantibody tests Antiphospholipid (aPL) antibodies Other SLE antibodies Myasthenia gravis antibodies Other differentiating antibodies Magnetic resonance imaging (MRI): features Other…

Autoantibody tests

  • Antiphospholipid (aPL) antibodies
  • Other SLE antibodies
  • Myasthenia gravis antibodies
  • Other differentiating antibodies

Magnetic resonance imaging (MRI): features

Other imaging modalities

Cerebrospinal fluid (CSF) analysis

Other investigations

References

  1. Zhou HQ, Zhang FC, Tian XP, et al. Clinical features and outcome of neuropsychiatric lupus in Chinese: analysis of 240 hospitalized patients. Lupus 2008; 17:93-99.
  2. Popescu A, Kao AH. Neuropsychiatric systemic lupus erythematosus. Curr Neuropharmacol 2011; 9:449-457.
  3. Magro-Checa C, Zirkzee EJ, Huizinga TW, Steup-Beekman GM. Management of neuropsychiatric systemic lupus erythematosus: current approaches and future perspectives. Drugs 2016; 76:459-483.
  4. Sarwar S, Mohamed AS, Rogers S, et al. Neuropsychiatric systemic lupus erythematosus: a 2021 update on diagnosis, management, and current challenges. Cureus 2021; 13:e17969.
  5. Emerson JS, Gruenewald SM, Gomes L, Lin MW, Swaminathan S. The conundrum of neuropsychiatric systemic lupus erythematosus: Current and novel approaches to diagnosis. Front Neurol 2023; 14:1111769.
  6. And 5 more. Subscribe to see the full list

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