Neurofibromatosis type 2 (NF2): management

Evidence-based neurology checklist on neurofibromatosis type 2 (nf2): management: Multidisciplinary management team Neurosurgeon Otolaryngologist Audiologist Neurologist Ophthalmologist Neuro-radiologist Neuro-oncologist Geneticist Surgical treatment Bevacizumab therapy: indications…

Multidisciplinary management team

  • Neurosurgeon
  • Otolaryngologist
  • Audiologist
  • Neurologist
  • Ophthalmologist
  • Neuro-radiologist
  • Neuro-oncologist
  • Geneticist

Surgical treatment

Bevacizumab therapy: indications

Investigational drugs

Synonym

References

  1. Evans DGR, Salvador H, Chang VY, et al. Cancer and central nervous system tumor surveillance in pediatric neurofibromatosis 2 and related disorders. Clin Cancer Res 2017; 23:e54-e61. 
  2. Plotkin SR, Merker VL, Halpin C, Jennings D, McKenna MJ, Harris GJ, Barker FG 2nd. Bevacizumab for progressive vestibular schwannoma in neurofibromatosis type 2: a retrospective review of 31 patients. Otol Neurotol 2012; 33:1046-1052.
  3. Farschtschi S, Merker VL, Wolf D, et al. Bevacizumab treatment for symptomatic spinal ependymomas in neurofibromatosis type 2. Acta Neurol Scand 2016; 133:475-480.
  4. Morris KA, Afridi SK, Evans DG, et al; on behalf of the UK NF2 Research Group. The response of spinal cord ependymomas to bevacizumab in patients with neurofibromatosis type 2. J Neurosurg Spine 2016; 16:1-9.
  5. Alanin MC, Klausen C, Caye-Thomasen P, et al. Effect of bevacizumab on intracranial meningiomas in patients with neurofibromatosis type 2-a retrospective case series. Int J Neurosci 2015; 26:1002-1006.
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