Mycophenolate

Evidence-based neurology checklist on mycophenolate: Indications Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) Multifocal motor neuropathy (MMN) Polymyositis Myasthenia gravis (MG) Contraindications Dose Precautions Monitoring blood tests Monitoring frequency Monitoring: others…

Indications

  • Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)
  • Multifocal motor neuropathy (MMN)
  • Polymyositis
  • Myasthenia gravis (MG)

Contraindications

Dose

Precautions

Monitoring blood tests

Monitoring frequency

Monitoring: others

Indications for stopping

References

  1. Gorson KC, Amato AA, Ropper AH. Efficacy of mycophenolate mofetil in patients with chronic immune demyelinating polyneuropathy. Neurology 2004; 63:715-717.
  2. Chaudhry V, Cornblath DR, Griffin JW, O'Brien R, Drachman DB. Mycophenolate mofetil: a safe and promising immunosuppressant in neuromuscular diseases. Neurology 2001; 56:94-96.
  3. Piepers S, Van den Berg-Vos R, Van der Pol WL, Franssen H, Wokke J, Van den Berg L. Mycophenolate mofetil as adjunctive therapy for MMN patients: a randomized, controlled trial. Brain 2007; 130:2004-2010.
  4. Pisoni CN, Cuadrado MJ, Khamashta MA, Hughes GR, D'Cruz DP. Mycophenolate mofetil treatment in resistant myositis. Rheumatology (Oxford) 2007; 46:516-518.
  5. Majithia V, Harisdangkul V. Mycophenolate mofetil (CellCept): an alternative therapy for autoimmune inflammatory myopathy. Rheumatology (Oxford) 2005; 44:386-389. 
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