Myasthenic crisis: management

Evidence-based neurology checklist on myasthenic crisis: management: Immunological management Intravenous immunoglobulin (IVIg) Plasma exchange (PE): this is probably better than IVIg Prednisolone Ciclosporin for long-term treatment: it is quicker acting than Azathioprine or Mycophenolate…

Immunological management

  • Intravenous immunoglobulin (IVIg)
  • Plasma exchange (PE): this is probably better than IVIg
  • Prednisolone
  • Ciclosporin for long-term treatment: it is quicker acting than Azathioprine or Mycophenolate
  • Thymectomy: when the patient is stable

Respiratory management

Nutritional management

Medical management

Predictors of ventilatory failure: the 20/30/40 rule

References

  1. Godoy DA, Mello LJ, Masotti L, Napoli MD. The myasthenic patient in crisis: an update of the management in Neurointensive Care Unit. Arq Neuropsiquiatr 2013; 71:627-639.
  2. Chaudhuri A, Behan PO. Myasthenic crisis. Q J Med 2009; 102:97-107.
  3. Wendell LC, Levine JM. Myasthenic crisis. Neurohospitalist 2011; 1:16-22.
  4. Claytor B, Cho SM, Li Y. Myasthenic crisis. Muscle Nerve 2023; 68:8-19.

Related checklists

Loading...