Myasthenia gravis (MG): cholinergic crisis

Evidence-based neurology checklist on myasthenia gravis (mg): cholinergic crisis: Description This is respiratory failure caused by cholinergic excess It is caused by cholinesterase inhibitors Neurological features Systemic features Investigation: Edrophonium test: benefit Differential diagnosis:…

Description

  • This is respiratory failure caused by cholinergic excess
  • It is caused by cholinesterase inhibitors

Neurological features

Systemic features

Investigation: Edrophonium test: benefit

Differential diagnosis: other causes of cholinergic crisis

Treatment

References

References

  1. Hetherington KA, Losek JD. Myasthenia gravis: myasthenia vs. cholinergic crisis. Pediatr Emerg Care 2005; 21:546-548. 
  2. Wendell LC, Levine JM. Myasthenic crisis. Neurohospitalist 2011; 1:16-22.
  3. Godoy DA, Mello LJ, Masotti L, Napoli MD. The myasthenic patient in crisis: an update of the management in Neurointensive Care Unit. Arq Neuropsiquiatr 2013; 71(9A):627-639.
  4. Waseem M, Perry C, Bomann S, Pai M, Gernsheimer J. Cholinergic crisis after rodenticide poisoning. West J Emerg Med 2010; 11:524-527.
  5. Azazh A. Severe organophosphate poisoning with delayed cholinergic crisis, intermediate syndrome and organophosphate induced delayed polyneuropathy on succession. Ethiop J Health Sci 2011; 21:203-208.
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