Myasthenia gravis (MG) treatment: pyridostigmine

Evidence-based neurology checklist on myasthenia gravis (mg) treatment: pyridostigmine: Efficacy Pyridostigmine showed better efficacy than placebo in a randomized control trial Dosing regime Precautions Side effects Treatment of side effects

Efficacy

  • Pyridostigmine showed better efficacy than placebo in a randomized control trial

Dosing regime

Precautions

Side effects

Treatment of side effects

References

  1. Skeie GO, Apostolski S, Evoli A, et al. Guidelines for treatment of autoimmune neuromuscular transmission disorders. Eur J Neurol 2010; 17:893-902.
  2. Sanders DB, Wolfe GI, Benatar M, et al. International consensus guidance for management of myasthenia gravis: executive summary. Neurology 2016; 87:419-425.
  3. Remijn-Nelissen L, Bakker WR, van den Hout WB, et al. Efficacy of pyridostigmine in myasthenia gravis: a randomized, double-blind, placebo-controlled crossover trial. Neurology 2026; 106:e214865.
  4. Donskov AO, Vinge L, Axelsen SM, Andersen H. Overactive bladder in patients with myasthenia gravis-A cross-sectional population-based study. Acta Neurol Scand 2021; 144:76-80.
  5. Ceccanti M, Libonati L, Ruffolo G, et al. Effects of 3,4-diaminopyridine on myasthenia gravis: Preliminary results of an open-label study. Front Pharmacol 2022; 13:982434.

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