Myasthenia gravis (MG) and anaesthesia

Evidence-based neurology checklist on myasthenia gravis (mg) and anaesthesia: Precautions Use neuromuscular monitoring Use deep inhalational anaesthesia Ensure train-of-four (TOF) of >90% before terminating anaesthesia Avoid mechanical ventilation if possible Anaesthetic agents and MG…

Precautions

  • Use neuromuscular monitoring
  • Use deep inhalational anaesthesia
  • Ensure train-of-four (TOF) of >90% before terminating anaesthesia
  • Avoid mechanical ventilation if possible

Anaesthetic agents and MG

Cholinesterase inhibitors and anaesthesia

Azathioprine and anaesthesia

Peri-operative pain control

Pre-operative optimisation of myasthenic control

Acronym

References

  1. Blichfeldt-Lauridsen L, Hansen BD. Anesthesia and myasthenia gravis. Acta Anaesthesiol Scand 2012; 56:17-22.
  2. Rudzka-Nowak A, Piechota M. Anaesthetic management of a patient with myasthenia gravis for abdominal surgery using sugammadex. Arch Med Sci 2011; 7:361-364.
  3. de Boer HD, van Egmond J, Driessen JJ, Booij LH. A new approach to anesthesia management in myasthenia gravis: reversal of neuromuscular blockade by sugammadex. Rev Esp Anestesiol Reanim 2010; 57:181-184.
  4. Claytor B, Cho SM, Li Y. Myasthenic crisis. Muscle Nerve 2023; 68:8-19.

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