Muscle magnetic resonance imaging (MRI): disease-specific patterns

Indications for MRI muscle

• Muscle trauma
• Inherited muscle diseases
• Inflammatory muscle diseases
• Neoplastic muscle diseases
• Monitoring disease progression

Duchenne muscular dystrophy (DMD): sites of atrophy and oedema

Duchenne muscular dystrophy (DMD): spared muscles

Dysferlinopathy (LGMD2B): sites of early fatty infiltration

Dysferlinopathy (LGMD2B): sites of later fatty infiltration

Sarcoglyconopathy (LGMD2C-2F): affected muscles

Myofibrillar myopathy (MFM)

SEPN1 myopathy

Non-dystrophic myotonias

Spinal muscular dystrophy 3b (SMA3b)

Myotonic dystrophy: early affected muscles

Becker muscular dystrophy (BMD)

Oculopharyngeal muscular dystrophy (OPMD)

References

1. Wattjes MP, Kley RA Fischer D. Neuromuscular imaging in inherited muscle diseases. Eur Radiol 2010; 20:2447-2460.
2. Theodorou DJ, Theodorou SJ, Kakitsubata Y. Skeletal muscle disease: patterns of MRI appearances. Br J Radiol 2012; 85:e1298-e1308.
3. Ortolan P, Zanato R, Coran A, Beltrame V, Stramare R. Role of radiologic imaging in genetic and acquired neuromuscular disorders. Eur J Transl Myol 2015; 25:5014.
4. Morrow JM, Sinclair CD, Fischmann A, et al. MRI biomarker assessment of neuromuscular disease progression: a prospective observational cohort study. Lancet Neurol 2016; 15:65-77.
5. Polavarapu K, Manjunath M, Preethish-Kumar V, et al. Muscle MRI in Duchenne muscular dystrophy: evidence of a distinctive pattern. Neuromuscul Disord 2016; 26:768-774.
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Related checklists

• Muscle magnetic resonance imaging (MRI): abnormal patterns
• Muscle magnetic resonance imaging (MRI): muscle-specific patterns
• Muscle ultrasound