Mpox: management

Evidence-based neurology checklist on mpox: management: Magnetic resonance imaging (MRI) Diffuse cerebral oedema Hyperintensity in the thalamus, brainstem and posterior parietal cortex Meningeal enhancement Longitudinally extensive central spinal cord lesions Cerebrospinal fluid (CSF) analysis…

Magnetic resonance imaging (MRI)

  • Diffuse cerebral oedema
  • Hyperintensity in the thalamus, brainstem and posterior parietal cortex
  • Meningeal enhancement
  • Longitudinally extensive central spinal cord lesions

Cerebrospinal fluid (CSF) analysis

Electroencephalogram (EEG)

Other investigations

Treatment

Predictors of severe disease

References

  1. Badenoch JB, Conti I, Rengasamy ER, et al. Neurological and psychiatric presentations associated with human monkeypox virus infection: a systematic review and meta-analysis. EClinicalMedicine 2022; 52:101644.
  2. Samaranayake L, Anil S. The monkeypox outbreak and implications for dental practice. Int Dent J 2022; 72:589-596. 
  3. Hasan S, Saeed S. Monkeypox disease: an emerging public health concern in the shadow of COVID-19 pandemic: an update. Trop Med Infect Dis 2022; 7:283.
  4. Sepehrinezhad A, Ashayeri Ahmadabad R, Sahab-Negah S. Monkeypox virus from neurological complications to neuroinvasive properties: current status and future perspectives. J Neurol 2022 (Online ahead of print).
  5. Pastula DM, Tyler KL. An overview of monkeypox virus and its neuroinvasive potential. Ann Neurol 2022; 92:527-531. 
  6. And 5 more. Subscribe to see the full list

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