Mpox: clinical features

Evidence-based neurology checklist on mpox: clinical features: Pathology Monkeypox infection is a Poxviridae zoonotic disease It belongs to the genus Orthopoxvirus The natural reservoirs are possibly small mammals and primates It is transmitted by close physical and sexual contact It is also…

Pathology

  • Monkeypox infection is a Poxviridae zoonotic disease
  • It belongs to the genus Orthopoxvirus
  • The natural reservoirs are possibly small mammals and primates
  • It is transmitted by close physical and sexual contact
  • It is also spread by respiratory droplets, blood, and semen
  • The incubation period is 7-21 days
  • It is a mild infection and most cases recover in weeks

Epidemiology

Prodromal features

Dermatological features

Systemic features

Neurological features

Psychiatric features

Differential diagnosis

References

  1. Badenoch JB, Conti I, Rengasamy ER, et al. Neurological and psychiatric presentations associated with human monkeypox virus infection: a systematic review and meta-analysis. EClinicalMedicine 2022; 52:101644.
  2. Samaranayake L, Anil S. The monkeypox outbreak and implications for dental practice. Int Dent J 2022; 72:589-596. 
  3. Hasan S, Saeed S. Monkeypox disease: an emerging public health concern in the shadow of COVID-19 pandemic: an update. Trop Med Infect Dis 2022; 7:283.
  4. Sepehrinezhad A, Ashayeri Ahmadabad R, Sahab-Negah S. Monkeypox virus from neurological complications to neuroinvasive properties: current status and future perspectives. J Neurol 2022 (Online ahead of print).
  5. Pastula DM, Tyler KL. An overview of monkeypox virus and its neuroinvasive potential. Ann Neurol 2022; 92:527-531. 
  6. And 3 more. Subscribe to see the full list

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