Motor neurone diseases (MND): gastrostomy

Evidence-based neurology checklist on motor neurone diseases (mnd): gastrostomy: Percutaneous endoscopic gastrostomy (PEG) It stabilises weight and prolongs survival in about 50% of patients The best outcomes are with young-onset age It is indicated when there is a 10% loss in baseline weight (but…

Percutaneous endoscopic gastrostomy (PEG)

  • It stabilises weight and prolongs survival in about 50% of patients
  • The best outcomes are with young-onset age
  • It is indicated when there is a 10% loss in baseline weight (but 5% has been suggested)
  • It is also helpful when there is a doubling of eating time
  • Recurrent cough and choking at meals also indicate the need for a PEG
  • It is only performed if the forced vital capacity (FVC) is ≥ 50%

Radiologically inserted gastrostomy (RIG)

References

  1. ProGas Study Group. Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study. Lancet Neurol 2015; 14:702-709. 
  2. Leigh PN, Abrahams S, Al-Chalabi A, et al. The management of motor neurone disease. JNNP 2003; 74(Suppl IV):iv32-iv47.
  3. Falcão de Campos C, de Carvalho M. Riluzole-induced recurrent pancreatitis. J Clin Neurosci 2017; 45:153-154.

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