Monoclonal gammopathy associated myopathies (MGAM)
Evidence-based neurology checklist on monoclonal gammopathy associated myopathies (mgam): Types Sporadic late-onset nemaline myopathy (SLONM) Light chain (AL) amyloidosis myopathy Scleromyxedema with associated myopathy Monoclonal gammopathy-associated glycogen storage myopathy (MGGSM) Onset…
Types
- Sporadic late-onset nemaline myopathy (SLONM)
- Light chain (AL) amyloidosis myopathy
- Scleromyxedema with associated myopathy
- Monoclonal gammopathy-associated glycogen storage myopathy (MGGSM)
Onset features
Clinical features
Creatinine kinase (CK)
Muscle biopsy: required stains
Other investigations
Treatment
References
- Soontrapa P, Jones FJS, Milone M, et al. Clinicopathologic features, pathogenesis, and treatment of monoclonal gammopathy-associated myopathies. Neurology 2025; 105:e214101.
- Moshe-Lilie O, Banks G, Medvedova E, Masri A, Chahin N. Coexisting sporadic late onset nemaline myopathy and AL amyloid myopathy - incidental or related? Neuromuscul Disord 2022; 32:533-538.
- Wang M, Lei L, Chen H, et al. Monoclonal gammopathy with both nemaline myopathy and amyloid myopathy. Neuromuscul Disord 2017; 27:942-946.
