Migraine prophylaxis: magnesium
Evidence-based neurology checklist on migraine prophylaxis: magnesium: Relationship of magnesium to migraine Migraine sufferers often have low magnesium Low magnesium promotes cortical spreading depression Low magnesium also impairs serotonin receptor function Benefit in magnesium in migraine…
Relationship of magnesium to migraine
- Migraine sufferers often have low magnesium
- Low magnesium promotes cortical spreading depression
- Low magnesium also impairs serotonin receptor function
Benefit in magnesium in migraine prophylaxis
Benefit of magnesium for acute migraine treatment
Dose of magnesium in migraine prophylaxis
Dose of magnesium in acute migraine treatment
Side effects
References
- Mauskop A, Varughese J. Why all migraine patients should be treated with magnesium. J Neural Transm (Vienna) 2012; 119:575-579.
- Gröber U, Schmidt J, Kisters K. Magnesium in prevention and therapy. Nutrients 2015; 7:8199-8226.
- von Luckner A, Riederer F. Magnesium in migraine prophylaxis-is there an evidence-based rationale? a systematic review. Headache 2018; 58:199-209.
- Chiu HY, Yeh TH, Huang YC, Chen PY. Effects of intravenous and oral magnesium on reducing migraine: a meta-analysis of randomized controlled trials. Pain Physician 2016; 19:E97-E112.
- Karimi N, Razian A, Heidari M. The efficacy of magnesium oxide and sodium valproate in prevention of migraine headache: a randomized, controlled, double-blind, crossover study. Acta Neurol Belg 2019; doi: 10.1007/s13760-019-01101-x (Epub ahead of print).
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