Migraine prophylaxis: botulinum toxin

Evidence-based neurology checklist on migraine prophylaxis: botulinum toxin: Indications Chronic migraine: it is effective, safe and well-tolerated Failure of 2-3 previous migraine prophylactic drugs Muscles injected Procedure: PREMT injection protocol Indicators of response Indications to stop…

Indications

  • Chronic migraine: it is effective, safe and well-tolerated
  • Failure of 2-3 previous migraine prophylactic drugs

Muscles injected

Procedure: PREMT injection protocol

Indicators of response

Indications to stop treatment

References

  1. Blumenfeld A, Silberstein SD, Dodick DW, Aurora SK, Turkel CC, Binder WJ. Method of injection of onabotulinumtoxin A for chronic migraine: a safe, well-tolerated, and effective treatment paradigm based on the PREEMPT clinical program. Headache 2010; 50:1406-1418.
  2. Bendtsen L, Sacco S, Ashina M, et al. Guideline on the use of onabotulinumtoxinA in chronic migraine: a consensus statement from the European Headache Federation. J Headache Pain 2018; 19:91.
  3. Diener HC, Dodick DW, Turkel CC, et al. Pooled analysis of the safety and tolerability of onabotulinumtoxinA in the treatment of chronic migraine. Eur J Neurol 2014; 21:851-859.

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