Migraine prophylaxis: evidenced options
Evidence-based neurology checklist on migraine prophylaxis: evidenced options: Betablockers: Propranolol The starting dose is 40mg daily It is increased by 40mg weekly The maintenance dose is 40-120mg bid Betablockers: others Topiramate Candesartan Frovatriptan Amitriptyline Valproate Flunarizine…
Betablockers: Propranolol
- The starting dose is 40mg daily
- It is increased by 40mg weekly
- The maintenance dose is 40-120mg bid
Betablockers: others
Topiramate
Candesartan
Frovatriptan
Amitriptyline
Valproate
Flunarizine
CGRP monoclonal antibodies
Dual therapy
Acronym
References
- Eigenbrodt AK, Ashina H, Khan S, et al. Diagnosis and management of migraine in ten steps. Nat Rev Neurol 2021; 17:501-514.
- Silberstein SD, Holland S, Freitag F, et al. Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology 2012; 78:1337-1345.
- MacGregor EA, Steiner TJ, Davies PTG. British Association for the Study of Headaches (BASH). Guidelines for all healthcare professionals in the diagnosis and management of migraine, tension-type, cluster and medication-overuse headache. September 2010.
- Sprenger T, Viana M, Tassorelli C. Current prophylactic medications for migraine and their potential mechanisms of action. Neurotherapeutics 2018; 15:313-323.
- Hovaguimian A, Roth J. Management of chronic migraine. BMJ 2022; 379:e067670.
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