MELAS stroke-like episodes (SLEs): clinical features

Evidence-based neurology checklist on melas stroke-like episodes (sles): clinical features: Pathology These are metabolic strokes They arise from focal breakdown of the blood-brain barrier Epidemiology Triggers Clinical features Differential diagnosis: other causes of SLEs Acronym

Pathology

  • These are metabolic strokes
  • They arise from focal breakdown of the blood-brain barrier

Epidemiology

Triggers

Clinical features

Differential diagnosis: other causes of SLEs

Acronym

References

  1. Finsterer J, Aliyev R. Metabolic stroke or stroke-like lesion: peculiarities of a phenomenon. J Neurol Sci 2020; 412:116726. 
  2. Finsterer J. Mitochondrial metabolic stroke: phenotype and genetics of stroke-like episodes. J Neurol Sci 2019; 400:135-141.
  3. Finsterer J. Therapeutic management of stroke-like episodes varies from that of encephalitis. Medicine (Baltimore) 2020; 99:e19141. 
  4. Martinez-Fernandez E, Gil-Peralta A, Garcia-Lozano R, et al. Mitochondrial disease and stroke. Stroke 2001; 32:2507-2510.
  5. Durrleman C, Grevent D, Aubart M, et al. Clinical and radiological description of 120 pediatric stroke-like episodes. Eur J Neurol 2023; 30:2051-2061.
  6. And 4 more. Subscribe to see the full list

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