Lennox Gastaut syndrome (LGS): treatment

Evidence-based neurology checklist on lennox gastaut syndrome (lgs): treatment: Early-stage drug treatments: especially for drop attacks Valproate: this may be of choice Felbamate Lamotrigine Topiramate Later drug treatment considerations Drug treatments to use with caution Interventional treatments

Early-stage drug treatments: especially for drop attacks

  • Valproate: this may be of choice
  • Felbamate
  • Lamotrigine
  • Topiramate

Later drug treatment considerations

Drug treatments to use with caution

Interventional treatments

References

  1. van Rijckevorsel K. Treatment of Lennox-Gastaut syndrome: overview and recent findings. Neuropsychiatr Dis Treat 2008: 4:1001-1019.
  2. Stafstrom CE. Update on the management of Lennox-Gastaut syndrome with a focus on rufinamide. Neuropsychiatr Dis Treat 2009; 5:547–551.
  3. Bourgeois BF, Douglass LM, Sankar R. Lennox-Gastaut syndrome: A consensus approach to differential diagnosis. Epilepsia 2014; 55(Suppl 4):4-9.
  4. Arzimanoglou A, French J, Blume WT, et al. Lennox-Gastaut syndrome: a consensus approach to diagnosis, assessment, management, and trial methodology. Lancet Neurol 2009; 8:82-93. 
  5. Zhang Y, Wang Y, Zhou Y, Zhang L, Yu L, Zhou S. Therapeutic effects of the ketogenic diet in children with Lennox-Gastaut syndrome. Epilepsy Res 2016; 128:176-180.
  6. And 5 more. Subscribe to see the full list

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