Lennox-Gastaut syndrome (LGS): clinical features
Evidence-based neurology checklist on lennox-gastaut syndrome (lgs): clinical features: Demographic features The onset is usually < 8 years: it is most frequently between ages 3-5 years It may present in adulthood Boys more often affected Infantile spasms (West syndrome) may precede LGS Primary…
Demographic features
- The onset is usually < 8 years: it is most frequently between ages 3-5 years
- It may present in adulthood
- Boys more often affected
- Infantile spasms (West syndrome) may precede LGS
Primary causes
Secondary causes
Diagnostic triad
Characteristic seizure types
Other seizure types
Other features
Differential diagnosis
References
- Roger J, Dravet C, Bureau M. The Lennox-Gastaut syndrome. Cleve Clin J Med 1989; 56(Suppl 2): S172-S180.
- van Rijckevorsel K. Treatment of Lennox-Gastaut syndrome: overview and recent findings. Neuropsychiatr Dis Treat 2008: 4:1001-1019.
- Bourgeois BF, Douglass LM, Sankar R. Lennox-Gastaut syndrome: A consensus approach to differential diagnosis. Epilepsia 2014; 55(Suppl 4):4-9.
- Arzimanoglou A, French J, Blume WT, et al. Lennox-Gastaut syndrome: a consensus approach to diagnosis, assessment, management, and trial methodology. Lancet Neurol 2009; 8:82-93.
- Zhou P, He N, Zhang JW, et al. Novel mutations and phenotypes of epilepsy-associated genes in epileptic encephalopathies. Genes Brain Behav 2018; doi: 10.1111/gbb.12456 (Epub ahead of print).
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