Immune mediated necrotising myopathy (IMNM): management

Evidence-based neurology checklist on immune mediated necrotising myopathy (imnm): management: Electromyogram (EMG) This is myopathic It may show myotonic discharges: especially in statin-induced cases Muscle biopsy Other investigations Cancer screening: indications Treatment options Synonym

Electromyogram (EMG)

  • This is myopathic
  • It may show myotonic discharges: especially in statin-induced cases

Muscle biopsy

Other investigations

Cancer screening: indications

Treatment options

Synonym

References

  1. Castro C, Gourley M. Diagnosis and treatment of inflammatory myopathy: issues and management. Ther Adv Musculoskel Dis 2012; 4:111-120.
  2. Grable-Esposito P, Katzberg HD, Greenberg SA, Srinivasan J, Katz J, Amato AA. Immune-mediated necrotizing myopathy associated with statins. Muscle Nerve 2010; 41:185-190.
  3. Selva-O'Callaghan A, Pinal-Fernandez I, Trallero-Araguás E, Milisenda JC, Grau-Junyent JM, Mammen AL. Classification and management of adult inflammatory myopathies. Lancet Neurol 2018; 17:816-828.
  4. Allenbach Y, Keraen J, Bouvier AM, et al. High risk of cancer in autoimmune necrotizing myopathies: usefulness of myositis specific antibody. Brain 2016; 139:2131-2135. 
  5. Kruse RL, Albayda J, Vozniak SO, et al. Therapeutic plasma exchange for the treatment of refractory necrotizing autoimmune myopathy. J Clin Apher 2022; 37:253-262. 
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