Immune mediated necrotising myopathy (IMNM): causes

Evidence-based neurology checklist on immune mediated necrotising myopathy (imnm): causes: Autoimmune Anti HMGCoA reductase: this is found in about a third of cases Anti SRP: this is present in about a quarter of cases Statins Paraneoplastic Viral causes CHKB congenital muscular dystrophy Other…

Autoimmune

  • Anti HMGCoA reductase: this is found in about a third of cases
  • Anti SRP: this is present in about a quarter of cases

Statins

Paraneoplastic

Viral causes

CHKB congenital muscular dystrophy

Other causes

Synonym

Acronyms

References

  1. Kassardjian CD, Lennon VA, Alfugham NB, Mahler M, Milone M. Clinical features and treatment outcomes of necrotizing autoimmune myopathy. JAMA Neurol 2015; 72:996-1003.
  2. Meriggioli MN. The clinical spectrum of necrotizing autoimmune myopathy: a mixed bag with blurred lines. JAMA Neurol 2015; 72:977-979. 
  3. Babu S, Li Y. Statin induced necrotizing myopathy. J Neurol Sci 2015; 351:13-17. 
  4. Mammen AL, Chung T, Christopher-Stine L, et al. Autoantibodies against 3-hydroxy-3-methylglutaryl-coenzyme A reductase in patients with statin-associated autoimmune myopathy. Arthritis Rheum 2011; 63:713-721.
  5. Babu S, Li Y. Statin induced necrotizing myopathy. J Neurol Sci 2015; 351:13-17. 
  6. And 12 more. Subscribe to see the full list

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