Ictal central apnea (ICA)

Evidence-based neurology checklist on ictal central apnea (ica): Demographic features This occurs in focal seizures It is more frequent in temporal lobe epilepsy (TLE) It is the only seizure feature in about 15% of cases It is linked to spread of the seizure to the contralateral temporal lobe…

Demographic features

  • This occurs in focal seizures
  • It is more frequent in temporal lobe epilepsy (TLE)
  • It is the only seizure feature in about 15% of cases
  • It is linked to spread of the seizure to the contralateral temporal lobe

Clinical features

Predictors of prolonged duration

Clinical implications

References

  1. Lacuey N, Zonjy B, Hampson JP, et al. The incidence and significance of periictal apnea in epileptic seizures. Epilepsia 2018; 59:573-582. 
  2. Micalizzi E, Vaudano AE, Giovannini G, Turchi G, Giunta L, Meletti S. Case report: ictal central apnea as first and overlooked symptom in temporal lobe seizures. Front Neurol 2021; 12:753860. 
  3. Seyal M, Bateman LM. Ictal apnea linked to contralateral spread of temporal lobe seizures: Intracranial EEG recordings in refractory temporal lobe epilepsy. Epilepsia 2009; 50:2557-2562.
  4. Nadkarni MA, Friedman D, Devinsky O. Central apnea at complex partial seizure onset. Seizure 2012; 21:555-558. 
  5. Nishimura Y, Saito Y, Kondo N, et al. Ictal central apnea and bradycardia in temporal lobe epilepsy complicated by obstructive sleep apnea syndrome. Epilepsy Behav Case Rep 2015; 4:41-44.
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