Frontotemporal dementia (FTD): management

Evidence-based neurology checklist on frontotemporal dementia (ftd): management: Selective serotonin reuptake inhibitors (SSRIs): indications Disinhibition Stereotypy Depression Inappropriate sexual behaviour Treatment of emotional fluctuations Potential treatments Other management approaches…

Selective serotonin reuptake inhibitors (SSRIs): indications

  • Disinhibition
  • Stereotypy
  • Depression
  • Inappropriate sexual behaviour

Treatment of emotional fluctuations

Potential treatments

Other management approaches

Investigational treatments

References

  1. Mendez MF, Lauterbach EC, Sampson SM, ANPA Committee on Research. An evidence-based review of the psychopathology of frontotemporal dementia: a report of the ANPA Committee on Research. J Neuropsychiatry Clin Neurosci 2008; 20:130-149.
  2. Boxer AL, Boeve BF. Frontotemporal dementia treatment: current symptomatic therapies and implications of recent genetic, biochemical, and neuroimaging studies. Alzheimer Dis Assoc Disord 2007; 21:S79-S87.
  3. Tsai RM, Boxer AL. Treatment of frontotemporal dementia. Curr Treat Options Neurol 2014; 16:319.
  4. Coleman KKL, Berry S, Cummings J, et al. Intranasal oxytocin for apathy in people with frontotemporal dementia (FOXY): a multicentre, randomised, double-blind, placebo-controlled, adaptive, crossover, phase 2a/2b superiority trial. Lancet Neurol 2025 (Online ahead of print).

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