Folate deficiency peripheral neuropathy (PN)
Evidence-based neurology checklist on folate deficiency peripheral neuropathy (pn): Causes of folate deficiency Alcoholism Dietary deficiency Drugs Hereditary folate malabsorption (HFM) Also see Neurochecklist: “Cerebral folate deficiency: causes” Clinical features Blood investigations…
Causes of folate deficiency
- Alcoholism
- Dietary deficiency
- Drugs
- Hereditary folate malabsorption (HFM)
- Also see Neurochecklist: “Cerebral folate deficiency: causes”
Clinical features
Blood investigations
Differential diagnosis
Treatment
References
- Koike H, Takahashi M, Ohyama K, et al. Clinicopathologic features of folate-deficiency neuropathy. Neurology 2015; 84:1026-1033.
- Manzoor M, Runcie J. Folate-responsive neuropathy: report of 10 cases. Br Med J 1976; 1:1176-1178.
- Steinschneider M, Sherbany A, Pavlakis S, Emerson R, Lovelace R, De Vivo DC. Congenital folate malabsorption: reversible clinical and neurophysiologic abnormalities. Neurology 1990; 40:1315.
- Shin DS, Mahadeo K, Min SH, et al. Identification of novel mutations in the proton-coupled folate transporter (PCFT-SLC46A1) associated with hereditary folate malabsorption. Mol Genet Metab 2011; 103:33-37.
