Epilepsy: seizure control

Evidence-based neurology checklist on epilepsy: seizure control: Seizure control rate Seizure control is achieved in 50% of cases with the first AED It is achieved in 30% with the second AED Eventual seizure control is achieved in about 20% of initially pharmaco-resistant cases Seizure recurrence…

Seizure control rate

  • Seizure control is achieved in 50% of cases with the first AED
  • It is achieved in 30% with the second AED
  • Eventual seizure control is achieved in about 20% of initially pharmaco-resistant cases

Seizure recurrence rate

Risk factors for seizure recurrence

Indications for specialist referral in poor seizure control

References

  1. Perucca E, Tomson T. The pharmacological treatment of epilepsy. Lancet Neurol 2011; 10:446-456.
  2. Seneviratne U. Management of the first seizure: an evidence based approach. Postgrad Med J 2009; 85:667-673.
  3. Hixson JD. Stopping antiepileptic drugs: when and why? Curr Treat Options Neurol 2010; 12:434-442.
  4. Berg AT, Shinnar S. Relapse following discontinuation of antiepileptic drugs: a meta-analysis. Neurology 1994; 44:601-608.
  5. Lossius MI, Hessen E, Mowinckel P, et al. Consequences of antiepileptic drug withdrawal: a randomized, double-blind study. Epilepsia 2008; 3:455-463.
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