Distal acquired demyelinating symmetric neuropathy (DADS)
Evidence-based neurology checklist on distal acquired demyelinating symmetric neuropathy (dads): Clinical features This is a distal and symmetrical variant of CIDP It is predominantly sensory but it may be sensory-motor Motor involvement is more evident on neurophysiology It may progress to…
Clinical features
- This is a distal and symmetrical variant of CIDP
- It is predominantly sensory but it may be sensory-motor
- Motor involvement is more evident on neurophysiology
- It may progress to classic CIDP
- It may present with allodynia
Types of DADS: DADS-M
Reported associations
Nerve conduction studies (NCS)
Nerve biopsy: features
Treatment
Acronym
References
- Liewluck T, Engelstad JK, Mauermann ML. Immunotherapy-responsive allodynia due to distal acquired demyelinating symmetric (DADS) neuropathy. Muscle Nerve 2016; 54:973-977.
- Mathey EK, Park SB, Hughes RA, et al. Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype. JNNP 2015; 86:973-985.
- Katz JS, Saperstein DS, Gronseth G, Amato AA, Barohn RJ. Distal acquired demyelinating symmetric neuropathy. Neurology 2000; 54:615-620.
- Leitch MM, Sherman WH, Brannagan TH 3rd. Distal acquired demyelinating symmetric polyneuropathy progressing to classic chronic inflammatory demyelinating polyneuropathy and response to fludarabine and cyclophosphamide. Muscle Nerve 2013; 47:292-296.
- Saperstein DS, Katz JS, Amato AA, Barohn RJ. Clinical spectrum of chronic acquired demyelinating polyneuropathies. Muscle Nerve 2001; 24:311-324.
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