Disease modifying treatments (DMTs): pre-treatment screening

Evidence-based neurology checklist on disease modifying treatments (dmts): pre-treatment screening: Tuberculosis screening Definite indications Considered indications Hepatitis B virus (HBV) screening Hepatitis C virus (HCV) screening HIV screening JC virus screening Aciclovir prophylaxis

Tuberculosis screening

  • Definite indications
  • Considered indications

Hepatitis B virus (HBV) screening

Hepatitis C virus (HCV) screening

HIV screening

JC virus screening

Aciclovir prophylaxis

References

  1. Epstein DJ, Dunn J, Deresinski S. Infectious complications of multiple sclerosis therapies: implications for screening, prophylaxis, and management. Open Forum Infect Dis 2018; 5:ofy174.
  2. Rae-Grant A, Day GS, Marrie RA, et al. Practice guideline recommendations summary: Disease-modifying therapies for adults with multiple sclerosis: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology 2018; 90:777-788.
  3. Chalmer TA, Baggesen LM, Nørgaard M, Koch-Henriksen N, Magyari M, Sorensen PS; Danish Multiple Sclerosis Group. Early versus later treatment start in multiple sclerosis: a register-based cohort study. Eur J Neurol 2018; 25:1262-e110.
  4. Kavaliunas A, Manouchehrinia A, Stawiarz L, et al. Importance of early treatment initiation in the clinical course of multiple sclerosis. Mult Scler 2017; 23:1233-1240.

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