Disease modifying treatments (DMTs): classification

Evidence-based neurology checklist on disease modifying treatments (dmts): classification: Interferons Interferon β 1a Interferon β 1b Pegylated interferon (PEG interferon) β-1a Monoclonal antibodies Oral agents Other agents Conventional first line DMTs for MS First line DMTs for aggressive…

Interferons

  • Interferon β 1a
  • Interferon β 1b
  • Pegylated interferon (PEG interferon) β-1a

Monoclonal antibodies

Oral agents

Other agents

Conventional first line DMTs for MS

First line DMTs for aggressive disease

Second line DMTs for aggressive disease

Newer DMTs

References

  1. Torkildsen Ø, Myhr KM, Bø L. Disease-modifying treatments for multiple sclerosis-a review of approved medications. Eur J Neurol 2016; 23(Suppl 1):18-27.
  2. Castro-Borrero W, Graves D, Frohman TC, et al. Current and emerging therapies in multiple sclerosis: a systematic review. Ther Adv Neurol Disord 2012; 5:205-220.
  3. Dargahi N, Katsara M, Tselios T, et al. Multiple sclerosis: immunopathology and treatment update. Brain Sci 2017; 7(7) pii: E78. 
  4. Rejdak K, Jackson S, Giovannoni G. Multiple sclerosis: a practical overview for clinicians. Br Med Bull 2010; 95:79-104.
  5. Rice CM. Disease modification in multiple sclerosis: an update. Pract Neurol 2014; 14:6-13.
  6. And 24 more. Subscribe to see the full list

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