Diabetic neuropathy: treatment
Evidence-based neurology checklist on diabetic neuropathy: treatment: Level B evidence Tricyclics Serotonin and norepinephrine reuptake inhibitors (SNRIs) Gabapentinoids Sodium channel blockers Level C evidence Insufficient evidence Contraindicated drugs Non-drug treatments Investigational…
Level B evidence
- Tricyclics
- Serotonin and norepinephrine reuptake inhibitors (SNRIs)
- Gabapentinoids
- Sodium channel blockers
Level C evidence
Insufficient evidence
Contraindicated drugs
Non-drug treatments
Investigational treatments
General recommendations
References
- Price R, Smith D, Franklin G, et al. Oral and topical treatment of painful diabetic polyneuropathy: practice guideline update summary: report of the AAN Guideline Subcommittee. Neurology 2022; 98:31-43.
- Bril V. Treatments of diabetic neuropathy. J Peripher Nerv Syst 2012; 17(Suppl):22-27.
- Xu L, Sun Z, Casserly E, Nasr C, Cheng J, Xu J. Advances in interventional therapies for painful diabetic neuropathy: a systematic review. Anesth Analg 2022; 134:1215-1228.
- D'Souza RS, Langford B, Dombovy-Johnson M, Abd-Elsayed A. Neuromodulation interventions for the treatment of painful diabetic neuropathy: a systematic review. Curr Pain Headache Rep 2022; 26:365-377.
- Reynolds EL, Russman D, Baskozos G, Eid S, Feldman EL, Bennett DLH, Callaghan BC. Physical activity decreases the likelihood of peripheral neuropathy in persons with diabetes. JNNP 2026; 97:464-468.
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