Diabetic neuropathy: investigations

Evidence-based neurology checklist on diabetic neuropathy: investigations: Immunoglobulins There is a high frequency of MGUS in diabetic neuropathy This is usually in the form of IgM and IgG Autonomic function tests Nerve function tests Corneal confocal microscopy (CCM) Acronym

Immunoglobulins

  • There is a high frequency of MGUS in diabetic neuropathy
  • This is usually in the form of IgM and IgG

Autonomic function tests

Nerve function tests

Corneal confocal microscopy (CCM)

Acronym

References

  1. Tavakoli M, Petropoulos IN, Malik RA. Corneal confocal microscopy to assess diabetic neuropathy: an eye on the foot. J Diabetes Sci Technol 2013; 7:1179-1189.
  2. Abraham A, Barnett C, Katzberg HD, Lovblom LE, Perkins BA, Bril V. High frequency of MGUS in DSP. Muscle Nerve 2018; 57:1018-1021. 
  3. Tavakoli M, Mitu-Pretorian M, Petropoulos IN, et al. Corneal confocal microscopy detects early nerve regeneration in diabetic neuropathy after simultaneous pancreas and kidney transplantation. Diabetes 2013; 62:254-260.
  4. Dhage S, Ferdousi M, Adam S, et al. Corneal confocal microscopy identifies small fibre damage and progression of diabetic neuropathy. Sci Rep 2021; 11:1859.

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