Cluster headache (CH): interventional prophylaxis

Conventional interventional treatments

• Greater occipital nerve block
• Occipital nerve stimulation
• Trigeminal ganglion radiofrequency ablation
• Trigeminal sensory gangliorhizolysis
• Gamma knife surgery
• Microvascular trigeminal nerve decompression
• Sphenopalatine ganglion ablation
• Sphenopalatine ganglion stimulation
• Deep brain stimulation (DBS)
• Vagus nerve stimulation (VNS)
• Stereotactic radiosurgery

Emerging interventional treatments

References

1. Gordon A, Roe T, Villar-Martínez MD, Moreno-Ajona D, Goadsby PJ, Hoffmann J. Effectiveness and safety profile of greater occipital nerve blockade in cluster headache: a systematic review. JNNP 2023 (Online ahead of print).
2. May A, Evers S, Goadsby PJ, et al. European Academy of Neurology guidelines on the treatment of cluster headache. Eur J Neurol 2023; 30:2955-2979.
3. Gantenbein AR, Lutz NJ, Riederer F, Sandor PS. Efficacy and safety of 121 injections of the greater occipital nerve in episodic and chronic cluster headache. Cephalalgia 2012; 32:630-634.
4. Fontaine D, Sol JC, Raoul S, et al. Treatment of refractory chronic cluster headache by chronic occipital nerve stimulation. Cephalalgia 2011; 31:1101-1105.
5. Leone M, Proietti Cecchini A, Messina G, Franzini A. Long-term occipital nerve stimulation for drug-resistant chronic cluster headache. Cephalalgia 2017; 37:756-763.
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Related checklists

• Cluster headache (CH): causes
• Cluster headache (CH): triggers and red flags
• Cluster headache (CH): clinical features
• Cluster headache (CH): co-morbid disorders
• Cluster headache (CH) in women
• Cluster headache (CH): acute treatment
• Cluster headache (CH): transitional prophylaxis
• Cluster headache (CH): chronic drug prophylaxis