Cluster headache (CH): causes

Evidence-based neurology checklist on cluster headache (ch): causes: Familial There is a family history in about 6 to 8% of cases This often involves female subjects The transmission pattern is mainly autosomal dominant Putative loci include DUSP10, CAPN2,ERTK, FTCDNL1, FHL5, WNT2, PLCE1, AND LRP1…

Familial

  • There is a family history in about 6 to 8% of cases
  • This often involves female subjects
  • The transmission pattern is mainly autosomal dominant
  • Putative loci include DUSP10, CAPN2,ERTK, FTCDNL1, FHL5, WNT2, PLCE1, AND LRP1
  • Familial cases manifest nasal blockage more frequently than non-familial cases
  • There is a high frequency of concurrent SUNCT

Vascular

Neoplastic

Infectious

Drug-induced

Dental

Developmental

Other causes

Lifestyle risk factors

Synonym

References

  1. Mainardi F, Trucco M, Maggioni F, Palestini C, Dainese F, Zanchin G. Cluster-like headache. A comprehensive reappraisal. Cephalalgia 2010; 30:399-412.
  2. O'Connor E, Simpson BS, Houlden H, Vandrovcova J, Matharu M. Prevalence of familial cluster headache: a systematic review and meta-analysis. J Headache Pain 2020; 21:37.
  3. Waung MW, Taylor A, Qualmann KJ, Burish MJ. Family history of cluster headache: a systematic review. JAMA Neurol 2020; 77:887-896.
  4. O'Connor E, Nikram E, Grangeon L, Danno D, Houlden H, Matharu M. The clinical characteristics of familial cluster headache. Cephalalgia 2022; 42:715-721. 
  5. Petersen AS, Lund N, Goadsby PJ, et al. Recent advances in diagnosing, managing, and understanding the pathophysiology of cluster headache. Lancet Neurol 2024; 23:712-724.
  6. And 7 more. Subscribe to see the full list

Related checklists

Loading...