Cerebral malaria: investigations

Evidence-based neurology checklist on cerebral malaria: investigations: Blood investigations Blood glucose Acidosis Blood film: thick and thin Microscopy Polymerase chain reaction (PCR): this is more sensitive than microscopy Emerging biomarkers Computed tomography (CT) head: features Magnetic…

Blood investigations

  • Blood glucose
  • Acidosis
  • Blood film: thick and thin
  • Microscopy
  • Polymerase chain reaction (PCR): this is more sensitive than microscopy

Emerging biomarkers

Computed tomography (CT) head: features

Magnetic resonance imaging (MRI) brain

Other investigations

Emerging ophthalmologic investigations

References

  1. Idro R, Jenkins NE, Newton CR. Pathogenesis, clinical features, and neurological outcome of cerebral malaria. Lancet Neurol 2005; 4:827-840.
  2. Newton CR, Hien TT, White N. Cerebral malaria. JNNP 2000; 69:433-441.
  3. Lucchi NW, Jain V, Wilson NO, Singh N, Udhayakumar V, Stiles JK. Potential serological biomarkers of cerebral malaria. Dis Markers 2011; 31:327-335. 
  4. Lovegrove FE, Tangpukdee N, Opoka RO, et al. Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. PLoS One 2009; 4: e4912. 
  5. Jain V, Lucchi NW, Wilson NO, et al. Plasma levels of angiopoietin-1 and -2 predict cerebral malaria outcome in Central India. Malar J 2011; 10:383.
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