Cerebral amyloid angiopathy (CAA): intracerebral haemorrhage (ICH)

Evidence-based neurology checklist on cerebral amyloid angiopathy (caa): intracerebral haemorrhage (ich): Types Peripheral Cortical Subcortical Predictors Bleed characteristics Risk of secondary bleeding Risk factors for recurrent ICH

Types

  • Peripheral
  • Cortical
  • Subcortical

Predictors

Bleed characteristics

Risk of secondary bleeding

Risk factors for recurrent ICH

References

  1. Charidimou A, Gang Q, Werring DJ. Sporadic cerebral amyloid angiopathy revisited: recent insights into pathophysiology and clinical spectrum. JNNP 2012; 83:124-137.
  2. Chamarthy MR, Kumar Y, Meszaros MD, Shah A, Rosovsky MA. Isolated central sulcus hemorrhage: a rare presentation most frequently associated with cerebral amyloid angiopathy. Case Rep Radiol 2012; 2012:574849. 
  3. Arndt P, Pfister M, Perosa V, et al. Cerebrospinal fluid amyloid-β biomarkers predict future hemorrhage in patients with cerebral amyloid angiopathy. Ann Neurol 2026 (Online ahead of print).
  4. Pasi M, Boulouis G, Fotiadis P, et al. Distribution of lacunes in cerebral amyloid angiopathy and hypertensive small vessel disease. Neurology 2017; 88:2162-2168. 
  5. Samarasekera N, Smith C, Al-Shahi Salman R. The association between cerebral amyloid angiopathy and intracerebral haemorrhage: systematic review and meta-analysis. JNNP 2012; 83:275-281.
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