Atogepant

Evidence-based neurology checklist on atogepant: Dose The dose is 10mg, 30mg or 60mg orally It is administered once or twice daily It is approved for acute and preventative migraine treatment Side effects

Dose

  • The dose is 10mg, 30mg or 60mg orally
  • It is administered once or twice daily
  • It is approved for acute and preventative migraine treatment

Side effects

References

  1. Kish T. Emerging therapies for patients with difficult-to-treat migraine. P T 2018; 43:616-621.
  2. Ashina M, Tepper SJ, Reuter U, et al. Once-daily oral atogepant for the long-term preventive treatment of migraine: Findings from a multicenter, randomized, open-label, phase 3 trial. Headache 2023; 63:79-88.
  3. Lipton RB, Pozo-Rosich P, Blumenfeld A, et al. Effect of atogepant for preventive migraine treatment on patient-reported outcomes in the randomized, double-blind, phase 3 ADVANCE Trial. Neurology 2022 (Online ahead of print).
  4. Tassorelli C, Nagy K, Pozo-Rosich P, et al. Safety and efficacy of atogepant for the preventive treatment of episodic migraine in adults for whom conventional oral preventive treatments have failed (ELEVATE): a randomised, placebo-controlled, phase 3b trial. Lancet Neurol 2024; 23:382-392.

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