Anti-seizure medications (ASMs): dosing summary

Evidence-based neurology checklist on anti-seizure medications (asms): dosing summary: Acetazolamide The dose is 4 mg/kg/day The typical adult dose is 500-1000 mg daily The standard formulation is administered in 3-4 divided doses The extended-release formulation is administered in 1 to 2 divided…

Acetazolamide

  • The dose is 4 mg/kg/day
  • The typical adult dose is 500-1000 mg daily
  • The standard formulation is administered in 3-4 divided doses
  • The extended-release formulation is administered in 1 to 2 divided doses

Brivaracetam

Carbamazepine

Clobazam

Clonazepam

Eslicarbazepine

Ethosuximide

Felbamate

Gabapentin

Lacosamide

Lamotrigine

Levetiracetam

Oxcarbazepine

Perampanel

Phenobarbitone

Phenytoin

Piracetam

Pregabalin

Primidone

Rufinamide in adults

Rufinamide in children ≥4 years

Stiripentol

Sulthiame

Tiagabine

Topiramate

Valproate

Vigabatrin

Zonisamide

Acronyms

Acetazolamide

Brivaracetam

Carbamazepine

Clobazam

Clonazepam

Eslicarbazepine

Ethosuximide

Felbamate

Gabapentin

Lacosamide

Lamotrigine

Levetiracetam

Oxcarbazepine

Perampanel

Phenobarbitone

Phenytoin

Piracetam

Pregabalin

Primidone

Rufinamide in adults

Rufinamide in children ≥4 years

Stiripentol

Sulthiame

Tiagabine

Topiramate

Valproate

Vigabatrin

Zonisamide

Acronyms

References

  1. Reiss WG, Oles KS. Acetazolamide in the treatment of seizures. Ann Pharmacother 1996; 30:514-519.
  2. Ferlazzo E, Russo E, Mumoli L, et al. Profile of brivaracetam and its potential in the treatment of epilepsy. Neuropsychiatr Dis Treat 2015; 11:2967-2973.
  3. Goldenberg MM. Overview of drugs used for epilepsy and seizures: etiology, diagnosis, and treatment. P T 2010; 35:392-415.
  4. Powell G, Saunders M, Marson AG. Immediate-release versus controlled-release carbamazepine in the treatment of epilepsy. Cochrane Database Syst Rev 2014; 2:CD007124.
  5. Gauthier AC, Mattson RH. Clobazam: a safe, efficacious, and newly rediscovered therapeutic for epilepsy. CNS Neurosci Ther 2015; 21:543-548. 
  6. And 35 more. Subscribe to see the full list

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