Anti neurochondrin cerebellar ataxia
Evidence-based neurology checklist on anti neurochondrin cerebellar ataxia: Pathogenesis This is an autoimmune non-paraneoplastic cerebellar ataxia It is caused by anti-neurochondrin (NCDN) antibodies These belong to the Medussa head antibody spectrum Clinical features Magnetic resonance imaging…
Pathogenesis
- This is an autoimmune non-paraneoplastic cerebellar ataxia
- It is caused by anti-neurochondrin (NCDN) antibodies
- These belong to the Medussa head antibody spectrum
Clinical features
Magnetic resonance imaging (MRI): features
Cerebrospinal fluid (CSF) analysis: features
Treatment
References
- Shelly S, Kryzer TJ, Komorowski L, et al. Neurochondrin neurological autoimmunity. Neurol Neuroimmunol Neuroinflamm 2019; pii: e612.
- Weihua Z, Haitao R, Fang F, Xunzhe Y, Jing W, Hongzhi G. Neurochondrin antibody serum positivity in three cases of autoimmune cerebellar ataxia. Cerebellum 2019; 18:1137-1142.
- Miske R, Gross CC, Scharf M, et al. Neurochondrin is a neuronal target antigen in autoimmune cerebellar degeneration. Neurol Neuroimmunol Neuroinflamm 2016; 4:e307.
