Anti FGFR3 autoimmune neuropathy

Evidence-based neurology checklist on anti fgfr3 autoimmune neuropathy: Pathology FGFR3 is involved in axonal development and regeneration Clinical features Co-morbid disorders Differential diagnosis Nerve conduction studies (NCS) Other investigations Treatment Acronym

Pathology

  • FGFR3 is involved in axonal development and regeneration

Clinical features

Co-morbid disorders

Differential diagnosis

Nerve conduction studies (NCS)

Other investigations

Treatment

Acronym

References

  1. Nagarajan E, Kang SA, Holmes C, Govindarajan R. Clinical features with anti fibroblast growth factor receptor 3 (FGFR3) antibody-related polyneuropathy: a retrospective study. BMC Neurol 2021; 21:74.
  2. Kovvuru S, Cardenas YC, Huttner A, Nowak RJ, Roy B. Clinical characteristics of fibroblast growth factor receptor 3 antibody-related polyneuropathy: a retrospective study. Eur J Neurol 2020; 27:1310-1318.
  3. Samara V, Sampson J, Muppidi S. FGFR3 antibodies in neuropathy: what to do with them? J Clin Neuromuscul Dis 2018; 20:35-40. 
  4. Antoine JC, Boutahar N, Lassablière F, et al. Antifibroblast growth factor receptor 3 antibodies identify a subgroup of patients with sensory neuropathy. JNNP 2015; 86:1347-1355.
  5. Theuriet J, Pegat A, Bernard E, Richard C, Camdessanche JP, Vukusic S. Acute relapsing ataxic sensory neuronopathy with anti-FGFR3 autoantibodies mimicking acute myelopathy. Rev Neurol (Paris) 2022; 178:626-627.

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