Agyrophilic grain disease (AGD): pathology

Evidence-based neurology checklist on agyrophilic grain disease (agd): pathology: Pathology This is a four-repeat tauopathy of older people It is sporadic: there are no familial cases it predominantly affects the limbic structures Pathological features Pathological stages Magnetic resonance…

Pathology

  • This is a four-repeat tauopathy of older people
  • It is sporadic: there are no familial cases
  • it predominantly affects the limbic structures

Pathological features

Pathological stages

Magnetic resonance imaging (MRI) brain

References

  1. Yokota O, Miki T, Ikeda C, et al. Neuropathological comorbidity associated with argyrophilic grain disease. Neuropathology 2018; 38:82-97. 
  2. Grinberg LT, Heinsen H. Argyrophilic grain disease: an update about a frequent cause of dementia. Dement Neuropsychol 2009; 3:2-7. 
  3. Togo T, Sahara N, Yen SH, et al. Argyrophilic grain disease is a sporadic 4-repeat tauopathy. J Neuropathol Exp Neurol 2002; 61:547-556.
  4. Ikeda C, Yokota O, Miki T, et al. Astrocytic tau pathologies in argyrophilic grain disease and related four-repeat tauopathies. Acta Med Okayama 2018; 72:211-221.
  5. Rodriguez RD, Grinberg LT. Argyrophilic grain disease: an underestimated tauopathy. Dement Neuropsychol 2015; 9:2-8. 
  6. And 3 more. Subscribe to see the full list

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