Acute disseminated encephalomyelitis (ADEM): clinical features

Evidence-based neurology checklist on acute disseminated encephalomyelitis (adem): clinical features: Epidemiological features There is a seasonal peak in winter and spring It usually affects children: especially infants There is a preceding infection in 2/3 of children and a half of adults…

Epidemiological features

  • There is a seasonal peak in winter and spring
  • It usually affects children: especially infants
  • There is a preceding infection in 2/3 of children and a half of adults

Clinical features

ADEM variants

Course and prognosis

References

  1. Bennetto L, Scolding N. Inflammatory/post-infectious encephalomyelitis. JNNP 2004; 75:i22-i28.
  2. Sonneville R, Klein I, de Broucker T, Wolff M. Post-infectious encephalitis in adults: diagnosis and management. J Infect 2009; 58:321-328.
  3. Hartung HP, Grossman RI. ADEM: distinct disease or part of the MS spectrum? Neurology 2001; 56:1257-1260.
  4. Koelman DL, Chahin S, Mar SS, et al. Acute disseminated encephalomyelitis in 228 patients: a retrospective, multicenter US study. Neurology 2016; 86:2085-2093.
  5. Parrish JB, Weinstock-Guttman B, Yeh EA. Cerebellar mutism in pediatric acute disseminated encephalomyelitis. Pediatr Neurol 2010; 42:259-266.
  6. And 3 more. Subscribe to see the full list

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